Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCR4 | P51679 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543669 | 0.88 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1USP2HTTPOLB | |
| SCHEMBL9289082 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1USP2HTTPOLB | |
| SCHEMBL8543401 | 0.82 | USP2 (0.47) | SMN1; SMN2ALDH1A1USP2HTTPOLB | |
| SCHEMBL8538321 | 0.81 | RXFP1 (0.48) | SMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8541053 | 0.78 | CYP3A4 (0.47) | ALDH1A1HTTP2RX7 | |
| SCHEMBL8544556 | 0.77 | MEN1 (0.43) | SMN1; SMN2ALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL8539565 | 0.76 | MEN1 (0.52) | SMN1; SMN2ALDH1A1POLBKDM4E | |
| SCHEMBL8542599 | 0.73 | ATM (0.44) | SMN1; SMN2ALDH1A1USP2KDM4EHSD17B10 | |
| SCHEMBL8589735 | 0.73 | CHRM2 (0.42) | SMN1; SMN2ALDH1A1HTTKDM4EHSD17B10 | |
| SCHEMBL8544484 | 0.71 | CHRM2 (0.41) | SMN1; SMN2ALDH1A1HTTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | claimed |