Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543277 | 0.97 | SLC6A2 (0.58) | SLC6A2S1PR1OXER1 | |
| SCHEMBL8544593 | 0.94 | SLC6A2 (0.59) | SLC6A2S1PR1 | |
| SCHEMBL8539214 | 0.88 | SLC6A2 (0.61) | SLC6A2 | |
| SCHEMBL8544814 | 0.86 | SLC6A2 (0.55) | SLC6A2 | |
| SCHEMBL8544200 | 0.86 | BCHE (0.53) | SLC6A2S1PR1OXER1 | |
| SCHEMBL8543976 | 0.85 | SLC6A2 (0.54) | SLC6A2 | |
| Hydrochloric Acid SCHEMBL8543736 | 0.85 | BCHE (0.52) | SLC6A2S1PR1OXER1 | |
| SCHEMBL8546112 | 0.85 | BCHE (0.52) | SLC6A2S1PR1OXER1 | |
| SCHEMBL8545510 | 0.78 | SLC6A2 (0.54) | SLC6A2 | |
| SCHEMBL8539705 | 0.77 | SLC6A2 (0.64) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |