Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544200 | 0.99 | BCHE (0.53) | BCHES1PR1SLC6A2OXER1SMO | |
| Hydrochloric Acid SCHEMBL8543736 | 0.98 | BCHE (0.52) | BCHES1PR1SLC6A2OXER1SMO | |
| SCHEMBL8539188 | 0.89 | BCHE (0.55) | BCHESLC6A2SMO | |
| SCHEMBL8544182 | 0.87 | BCHE (0.67) | BCHES1PR1SLC6A2ASAH1NAMPT | |
| SCHEMBL8543077 | 0.86 | BCHE (0.68) | BCHESLC6A2ASAH1NAMPT | |
| SCHEMBL8544945 | 0.85 | SLC6A2 (0.57) | S1PR1SLC6A2OXER1 | |
| SCHEMBL8543277 | 0.82 | SLC6A2 (0.58) | S1PR1SLC6A2OXER1 | |
| SCHEMBL9738698 | 0.81 | BCHE (0.70) | BCHESLC6A2 | |
| Hydrochloric Acid SCHEMBL9671917 | 0.80 | BCHE (0.69) | BCHESLC6A2 | |
| SCHEMBL8544593 | 0.79 | SLC6A2 (0.59) | S1PR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |