Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 10/20 | 0.67 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076954 | 0.94 | GRIN2B (0.59) | GRIN2BGRIN1MAPTL3MBTL1CES2 | |
| SCHEMBL5075641 | 0.88 | GRIN2B (0.63) | GRIN2BGRIN1NOS2NPC1 | |
| SCHEMBL11094429 | 0.84 | GRIN2B (0.57) | GRIN2BGRIN1CES2CES1NOS2 | |
| SCHEMBL8548012 | 0.81 | SCN2A (0.55) | GRIN2BGRIN1L3MBTL1CES2CES1 | |
| SCHEMBL27780168 | 0.80 | GRIN2B (0.65) | GRIN2BGRIN1MAPTL3MBTL1TAAR1 | |
| SCHEMBL11097294 | 0.79 | GRIN2B (0.54) | GRIN2BGRIN1NOS2RAB9A | |
| SCHEMBL5236050 | 0.78 | TSHR (0.52) | GRIN2BGRIN1L3MBTL1CES2CES1 | |
| SCHEMBL29157285 | 0.78 | GRIN2B (0.47) | GRIN2BGRIN1L3MBTL1NOS2POLB | |
| SCHEMBL30762058 | 0.76 | SCN2A (0.49) | GRIN2BGRIN1CES2CES1NOS2 | |
| SCHEMBL30389865 | 0.76 | SCN2A (0.49) | GRIN2BGRIN1CES2CES1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671385-B1 | Method for handling (2-alkyl) acryloyl isocyanate, method for producing (2-alkyl)acryloyl isocyanate, heterocyclic compound, and method for producing heterocyclic compound | NIPPON PAINT CO LTD (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5663423-A | Method for handling (2-alkyl) (acryloyl) isocyanate, method for stabilizing (2-alkyl) (acryloyl) isocyanate, method for producing (2-alkyl) (acryloyl) isocyanate, heterocyclic compound, and method for producing heterocyclic compound | NIPPON PAINT CO., LTD (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5532360-A | REACTING WITH AZOMETHINE COMPOUND TO FORM HETEROCYCLIC COMPOUND | NIPPON PAINT CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0671385-A1 | Method for handling (2-alkyl) acryloyl isocyanate, method for producing (2-alkyl)acryloyl isocyanate, heterocyclic compound, and method for producing heterocyclic compound | Nippon Paint Co., Ltd. (JP) | 1995-09-13 | — | — | EP | disclosed |