Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724745 | 0.97 | SRD5A1 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL8723340 | 0.96 | HSD17B7 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL8725556 | 0.96 | HSD17B7 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL8723334 | 0.96 | HSD17B7 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL8723337 | 0.96 | HSD17B7 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL8725551 | 0.96 | HSD17B7 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL8725548 | 0.96 | HSD17B7 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL8724850 | 0.86 | SRD5A1 (0.55) | SRD5A1SRD5A2 | |
| SCHEMBL5069448 | 0.86 | SRD5A1 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL8525804 | 0.86 | HSD17B7 (0.53) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760045-A | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. (US) | 1998-06-02 | — | — | US | disclosed |
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5510351-A | PREGNANE ENZYME INHIBITOR FOR TREATING SKIN DISORDER, BALDNESS, PROSTATIC CANCER | MERCK & CO., INC. (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0646007-A4 | — | — | 1995-04-26 | — | — | EP | disclosed |
| EP-0646007-A1 | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17-g(b)-SUBSTITUTED-4-AZA-5-g(a)-ANDROSTAN-3-ONES AS 5-g(a)-REDUCTASE INHIBITORS. | MERCK & CO INC (US) | 1995-04-05 | — | — | EP | disclosed |
| WO-1993023039-A1 | SUBSTITUTED 4-AZA-5A-ANDROSTAN-ONES AS 5A-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| WO-1993023050-A1 | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | disclosed |