Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | GALR3 | O60755 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329417 | 0.84 | POLB (0.53) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL8547111 | 0.83 | KMT2A (0.66) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL8542446 | 0.83 | MAPT (0.53) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL8543251 | 0.83 | MAPT (0.53) | MAPTLMNAPOLBGALR3NOD2 | |
| SCHEMBL8542584 | 0.82 | KMT2A (0.60) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL8544576 | 0.82 | F2 (0.68) | LMNAKDM4EHSD17B10GAA | |
| SCHEMBL7333893 | 0.77 | KMT2A (0.68) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL7329347 | 0.77 | KMT2A (0.70) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL7329809 | 0.77 | F2 (0.70) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL8548369 | 0.76 | F2 (0.64) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |