Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542584 | 0.90 | KMT2A (0.60) | F2POLBKMT2AMEN1LMNA | |
| SCHEMBL7333893 | 0.89 | KMT2A (0.68) | F2POLBKMT2AMEN1LMNA | |
| SCHEMBL7329347 | 0.87 | KMT2A (0.70) | F2POLBKMT2AMEN1LMNA | |
| SCHEMBL8546878 | 0.82 | F2 (1.00) | F2 | |
| SCHEMBL7335396 | 0.82 | F2 (0.60) | F2POLBKMT2AMEN1LMNA | |
| SCHEMBL8547111 | 0.82 | KMT2A (0.66) | F2POLBKMT2AMEN1LMNA | |
| SCHEMBL7336072 | 0.79 | LMNA (0.59) | F2POLBKMT2AMEN1LMNA | |
| SCHEMBL7334961 | 0.79 | MAPT (0.62) | POLBKMT2AMEN1LMNANOD2 | |
| SCHEMBL7329417 | 0.77 | POLB (0.53) | F2POLBKMT2AMEN1LMNA | |
| SCHEMBL8545271 | 0.77 | MAPT (0.63) | POLBKMT2AMEN1LMNANOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |