Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515239 | 0.75 | MAOA (0.69) | PTPN1MAOAMAOBTEKMEN1 | |
| SCHEMBL9588537 | 0.74 | PTPN1 (0.76) | PTPN1MAOAMAOBTEKMEN1 | |
| SCHEMBL11322423 | 0.69 | PTPN1 (1.00) | PTPN1MAOAMAOBTEKMEN1 | |
| SCHEMBL28166599 | 0.67 | PTPN1 (0.42) | PTPN1MAOAMAOBTEKMEN1 | |
| SCHEMBL27623517 | 0.66 | MAOA (0.57) | PTPN1MAOAMAOBCYP1A2CYP2C9 | |
| SCHEMBL28800705 | 0.66 | CYP2C9 (0.47) | PTPN1MAOAMAOBTEKMEN1 | |
| SCHEMBL17969811 | 0.66 | PTPN1 (0.62) | PTPN1MAOAMAOBTEKMEN1 | |
| SCHEMBL16938333 | 0.65 | BACE1 (0.57) | PTPN1MAOAMAOBMEN1NSD2 | |
| SCHEMBL1872240 | 0.64 | MAOA (1.00) | PTPN1MAOAMAOBTEKPARK7 | |
| SCHEMBL27936013 | 0.64 | PTPN1 (0.56) | PTPN1MAOAMAOBTEKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827501-A | INERT TRIARYLMETHYL FREE RADICAL CONTRAST AGENTS FOR ELECTRON SPIN RESONANCE (ESR) ENHANCED MAGNETIC RESONANCE (EMR) IMAGING | NYCOMED IMAGING AS (NO) | 1998-10-27 | — | — | US | disclosed |
| US-5599522-A | CONTRAST ENHANCING AGENTS | NYCOMED IMAGING AS (NO) | 1997-02-04 | — | — | US | disclosed |
| EP-0515458-B1 | TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI | NYCOMED INNOVATION AB (SE) | 1995-08-23 | — | — | EP | disclosed |
| EP-0515458-A1 | TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI. | HAFSLUND NYCOMED INNOVATION (SE) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991012024-A1 | TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI | HAFSLUND NYCOMED INNOVATION AB (SE) | 1991-08-22 | — | — | WO | disclosed |