SCHEMBL8545318

SCHEMBL8545318

Cc1cc(Cl)nc(Cl)c1S

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
LMNA P02545 2/20 0.34
TAAR1 Q96RJ0 1/20 0.34
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
MAPT P10636 1/20 0.32
MPI P34949 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10412144 0.81 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2MAPK1KDM4EKMT2A
SCHEMBL31396216 0.75 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2MAPK1KDM4ECYP3A4
SCHEMBL3752930 0.75 CYP3A4 (0.40) ALDH1A1SMN1; SMN2MAPK1KDM4ECYP3A4
SCHEMBL11985859 0.75 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2MAPK1KDM4ECYP3A4
SCHEMBL23797878 0.71 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2MAPK1KDM4ECYP3A4
SCHEMBL31178437 0.71 KMT2A (0.42) ALDH1A1SMN1; SMN2MAPK1KDM4ECYP3A4
SCHEMBL30421541 0.71 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2MAPK1KDM4ECYP3A4
SCHEMBL26705124 0.71 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2MAPK1KDM4ECYP3A4
SCHEMBL5746102 0.71 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2MAPK1KDM4ECYP3A4
SCHEMBL3752925 0.70 KDM4E (0.39) ALDH1A1SMN1; SMN2MAPK1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693490-B1 2-Phenoxy-6-thienylmethyloxypyridine derivative, process for producing the same, and herbicidal composition KUREHA CHEMICAL IND CO LTD (JP) 1998-09-09 EP disclosed
US-5624942-A 2-phenoxy-6-thienylmethyloxypyridine derivative and herbicidal composition containing same KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-04-29 US disclosed
EP-0693490-A1 2-Phenoxy-6-thienylmethyloxypyridine derivative, process for producing the same, and herbicidal composition KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-24 EP disclosed