Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545463 | 1.00 | RXRA (0.35) | RXRARXRBRXRGPOLBKMT2A | |
| SCHEMBL8870887 | 0.89 | POLB (0.40) | RXRARXRBRXRGPOLBKMT2A | |
| SCHEMBL8870889 | 0.89 | POLB (0.40) | RXRARXRBRXRGPOLBKMT2A | |
| SCHEMBL8543686 | 0.83 | POLB (0.34) | POLBKMT2AMEN1NPC1NFKB1 | |
| SCHEMBL8543683 | 0.83 | POLB (0.34) | POLBKMT2AMEN1NPC1NFKB1 | |
| SCHEMBL8620116 | 0.83 | POLB (0.35) | POLBKMT2AMEN1NPC1NFKB1 | |
| SCHEMBL8620112 | 0.83 | POLB (0.35) | POLBKMT2AMEN1NPC1NFKB1 | |
| SCHEMBL8544133 | 0.83 | POLB (0.34) | POLBKMT2AMEN1NPC1NFKB1 | |
| SCHEMBL8544135 | 0.83 | POLB (0.34) | POLBKMT2AMEN1NPC1NFKB1 | |
| SCHEMBL8899776 | 0.82 | RXRA (0.37) | RXRARXRBRXRGKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818455-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-01-14 | — | — | EP | disclosed |