Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859491 | 0.85 | CNR2 (0.52) | CNR2KLK5SSTR4SSTR1TRPA1 | |
| SCHEMBL27597715 | 0.76 | KLK5 (0.46) | CNR2KLK5SSTR4SSTR1TRPA1 | |
| SCHEMBL4353465 | 0.74 | KLK5 (0.51) | CNR2KLK5SSTR4SSTR1TRPA1 | |
| SCHEMBL28114917 | 0.73 | FFAR1 (0.42) | CNR2KLK5SSTR4SSTR1TRPA1 | |
| SCHEMBL761986 | 0.73 | KLK5 (0.50) | CNR2KLK5SSTR4SSTR1TRPA1 | |
| SCHEMBL27220785 | 0.73 | KLK5 (0.53) | CNR2KLK5SSTR4SSTR1TRPA1 | |
| SCHEMBL28855596 | 0.72 | KLK5 (0.47) | CNR2KLK5SSTR4SSTR1TRPA1 | |
| SCHEMBL28198079 | 0.71 | KLK5 (0.49) | CNR2KLK5SSTR4SSTR1TRPA1 | |
| SCHEMBL5716801 | 0.71 | KLK5 (0.49) | CNR2KLK5SSTR4SSTR1TRPA1 | |
| SCHEMBL2230387 | 0.71 | KLK5 (0.49) | CNR2KLK5SSTR4SSTR1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804431-A4 | GLYCOPROTEIN IIb/IIIa ANTAGONISTS | LILLY CO ELI (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0804431-A1 | GLYCOPROTEIN IIb/IIIa ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-11-05 | — | — | EP | disclosed |