Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP12 | P39900 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545583 | 0.95 | TDP1 (0.58) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL24343448 | 0.88 | TDP1 (0.54) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL15987451 | 0.88 | KMT2A (0.54) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL28050845 | 0.88 | TDP1 (0.54) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL13269161 | 0.85 | TDP1 (0.51) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL14905944 | 0.85 | TDP1 (0.51) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL25764435 | 0.84 | TDP1 (0.50) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL24412402 | 0.84 | TDP1 (0.46) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL6617909 | 0.83 | TDP1 (0.49) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL25725335 | 0.83 | CASP3 (0.67) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210032403-A1 | SQUARIC ACID-BASED POLYMERS, THEIR MANUFACTURING PROCESSES AND THEIR USES | HYDRO-QUéBEC (CA) | 2021-02-04 | — | — | US | disclosed |
| EP-0719774-B1 | A method for production of dibenzoxazolyl thiophenes | SUMITOMO SEIKA CHEMICALS (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0719774-A1 | A method for production of dibenzoxazolyl thiophenes | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5310940-A | Sulfiding, cyclization | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5221749-A | Reacting a thiophene,2,5-dicarboxylic acid diester with a 2-aminophenol in the presence of an acid catalyst | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| US-5093504-A | PRODUCTION OF THIOPHENE-2,5-DICARBOXYLIC ACID DIESTERS, TETRAHYDROTHIOPHENE-2,5-DICARBOXYLIC ACID DIESTERS AND DIBENZOXAZOLYLTHIOPHENES | SUMITOMO SEIKA CHEMICALS, CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0387725-A2 | Production of thiophene-2,5-dicarboxylic acid diesters and tetrahydrothiophene-2,5-dicarboxylic acid diesters | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |