Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 14/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578636 | 0.94 | EPHX2 (0.39) | EPHX2NR1H4MEN1KMT2ARAB9A | |
| SCHEMBL8592166 | 0.94 | EPHX2 (0.42) | EPHX2NR1H4MEN1KMT2ARAB9A | |
| SCHEMBL8593315 | 0.94 | LSS (0.36) | EPHX2HDAC3HDAC6 | |
| SCHEMBL8576986 | 0.93 | EPHX2 (0.42) | EPHX2NR1H4MEN1KMT2ARAB9A | |
| SCHEMBL8593156 | 0.92 | EPHX2 (0.39) | EPHX2NR1H4MEN1KMT2ARAB9A | |
| SCHEMBL8544471 | 0.92 | NPC1 (0.33) | MEN1KMT2ARAB9ANPC1CYP1A2 | |
| SCHEMBL8593316 | 0.92 | MCHR1 (0.37) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8590952 | 0.91 | NPC1 (0.41) | EPHX2NR1H4MEN1KMT2ARAB9A | |
| SCHEMBL8592260 | 0.91 | EPHX2 (0.36) | EPHX2NR1H4MEN1KMT2ARAB9A | |
| SCHEMBL8575127 | 0.90 | EPHX2 (0.34) | EPHX2NR1H4MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328085-B2 | Heterocyclic compounds and expansion agents for hematopoietic stem cells | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-05-03 | — | — | US | disclosed |
| US-20120128640-A1 | HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120128640-A1 | HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS | HCLS1, RUNX1, RCC1 | EPHX2 3254/4885NR1H4 767/4885MEN1 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.