Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.55 |
| ▸ | FABP3 | P05413 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086389 | 0.89 | MAPK1 (0.49) | PTGER1FABP3FABP4FABP5MAPK1 | |
| SCHEMBL1305739 | 0.87 | PTGER1 (0.61) | PTGER1FABP3FABP4FABP5SGMS2 | |
| SCHEMBL15298795 | 0.85 | PTGER1 (0.59) | PTGER1FABP3FABP4FABP5SGMS2 | |
| SCHEMBL23536856 | 0.83 | PTGER1 (0.60) | PTGER1SGMS2MAPTMAPK1TDP1 | |
| SCHEMBL5501764 | 0.80 | SCN9A (0.59) | PTGER1L3MBTL1MEN1KMT2AMRGPRX4 | |
| SCHEMBL29502881 | 0.80 | SCN9A (0.59) | PTGER1L3MBTL1MEN1KMT2AMRGPRX4 | |
| SCHEMBL29244980 | 0.79 | PTGER1 (0.59) | PTGER1SGMS2MAPTMAPK1TDP1 | |
| SCHEMBL8489879 | 0.79 | MAPT (0.57) | PTGER1SGMS2MAPTMAPK1TDP1 | |
| SCHEMBL7908707 | 0.78 | MCL1 (0.54) | PTGER1FOLH1MEN1KMT2AALDH1A1 | |
| SCHEMBL477006 | 0.78 | ALDH1A1 (0.59) | TDP1MEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | claimed |