Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538300 | 0.94 | GRIN2B (0.54) | HRH3GRIN2BSIGMAR1CCR3 | |
| SCHEMBL9030985 | 0.93 | HRH3 (0.51) | HRH3GRIN2BSIGMAR1CCR3 | |
| Hydrochloric Acid SCHEMBL8546852 | 0.93 | GRIN2B (0.53) | HRH3GRIN2BSIGMAR1CCR3 | |
| SCHEMBL8539454 | 0.92 | HRH3 (0.51) | HRH3GRIN2BSIGMAR1CCR3 | |
| SCHEMBL8545375 | 0.91 | SIGMAR1 (0.59) | HRH3GRIN2BSIGMAR1CCR3 | |
| SCHEMBL8541020 | 0.88 | GRIN2B (0.55) | HRH3GRIN2BSIGMAR1CCR3 | |
| SCHEMBL8545842 | 0.86 | CCR3 (0.56) | HRH3CCR3 | |
| SCHEMBL8699420 | 0.86 | SLC6A2 (0.48) | CYP19A1 | |
| SCHEMBL8543346 | 0.83 | SIGMAR1 (0.63) | SIGMAR1CYP19A1 | |
| SCHEMBL8540177 | 0.82 | CYP19A1 (0.49) | SIGMAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |