Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017634 | 0.79 | SMN1; SMN2 (0.55) | HPGDHSD17B10KCNA5GAASMN1; SMN2 | |
| SCHEMBL7089958 | 0.77 | KCNA5 (0.46) | KCNA5GAASMN1; SMN2CYP19A1ROCK2 | |
| SCHEMBL8327525 | 0.75 | GAA (0.34) | HPGDHSD17B10GAASMN1; SMN2CYP3A4 | |
| SCHEMBL1921464 | 0.75 | CYP19A1 (0.46) | HPGDGAASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL8324021 | 0.73 | TSHR (0.56) | HPGDHSD17B10L3MBTL1CYP3A4ALDH1A1 | |
| SCHEMBL7666179 | 0.73 | CYP1A2 (0.43) | SMN1; SMN2LMNACYP3A4CYP2D6SLC6A2 | |
| SCHEMBL23489766 | 0.73 | GAA (0.39) | HPGDHSD17B10GAASMN1; SMN2CYP3A4 | |
| SCHEMBL31473883 | 0.73 | GAA (0.39) | HPGDHSD17B10GAASMN1; SMN2CYP3A4 | |
| SCHEMBL17318479 | 0.73 | GAA (0.39) | HPGDHSD17B10GAASMN1; SMN2CYP3A4 | |
| SCHEMBL8546018 | 0.71 | TNF (0.38) | HPGDHSD17B10KCNA5GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695292-B1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LTD (GB) | 1998-02-25 | — | — | EP | disclosed |
| US-5585327-A | PRE- AND POST-EMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| EP-0695292-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024106-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |
| US-5308826-A | Pre- and postemergence herbicides; controlling weeds, particularly broad leaf plants and grasses | ZENECA LIMITED (GB) | 1994-05-03 | — | — | US | disclosed |