Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327409 | 0.79 | NPC1 (0.38) | KDM4EALDH1A1MAPTSMN1; SMN2RBP4 | |
| SCHEMBL30903830 | 0.79 | ACP3 (0.50) | ACP3CNR2P2RX7ALDH1A1GAA | |
| SCHEMBL9776265 | 0.79 | ACP3 (0.50) | ACP3CNR2P2RX7ALDH1A1GAA | |
| SCHEMBL12317610 | 0.76 | ACP3 (0.44) | ACP3CNR2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL8548980 | 0.76 | ACP3 (0.38) | TNFACP3CNR2P2RX7KCNA5 | |
| SCHEMBL9028689 | 0.75 | SCN9A (0.37) | TNFTYK2CNR2RBP4SLC22A12 | |
| SCHEMBL8745920 | 0.75 | PIEZO1 (0.38) | TNFACP3CNR2KCNA5GAA | |
| SCHEMBL8017634 | 0.74 | SMN1; SMN2 (0.55) | ACP3HPGDHSD17B10KCNA5ALDH1A1 | |
| SCHEMBL9028582 | 0.74 | SCN9A (0.40) | TNFTYK2CNR2P2RX7SLC22A12 | |
| SCHEMBL9030025 | 0.74 | GPBAR1 (0.38) | TYK2MAPTGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695292-B1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LTD (GB) | 1998-02-25 | — | — | EP | disclosed |
| US-5585327-A | PRE- AND POST-EMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| EP-0695292-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024106-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |
| US-5308826-A | Pre- and postemergence herbicides; controlling weeds, particularly broad leaf plants and grasses | ZENECA LIMITED (GB) | 1994-05-03 | — | — | US | disclosed |