Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045982 | 0.79 | HPGD (0.35) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8542718 | 0.78 | HTT (0.44) | ALDH1A1 | |
| SCHEMBL8562622 | 0.77 | — | — | |
| SCHEMBL8542730 | 0.77 | TP53 (0.43) | ALDH1A1HPGD | |
| SCHEMBL8542939 | 0.77 | MLYCD (0.40) | ALDH1A1 | |
| SCHEMBL7046884 | 0.74 | — | — | |
| SCHEMBL10998680 | 0.72 | — | — | |
| SCHEMBL969859 | 0.72 | TSHR (0.33) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1934622 | 0.72 | HDAC2 (0.32) | HPGDSMN1; SMN2 | |
| SCHEMBL3939619 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845459-A1 | Azetidinone derivatives useful in the preparation of carbapenem antibiotics | Sankyo Company Limited (JP) | 1998-06-03 | — | — | EP | disclosed |
| US-5719275-A | REACTING SILYL ENOL ETHER WITH AZETIDINONE DERIVATIVE TO FORM INTERMEDIATE FOR PENICILLIN-TYPE ANTIBIOTIC | SANKYO COMPANY, LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5681951-A | REACTING PENICILLIN DERIVATIVE HAVING SULFINYL OR SULFONYL GROUP IN 2 POSITION WITH SUBSTITUTED MERCAPTAN IN PRESENCE OF SALT OF GROUP IIA OR IIIA ELEMENT | SANKYO COMPANY, LIMITED (JP) | 1997-10-28 | — | — | US | disclosed |
| US-5614624-A | THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5541317-A | PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS | SANKYO COMPANY, LIMITED (JP) | 1996-07-30 | — | — | US | disclosed |
| EP-0516486-A2 | Azetidinone derivatives useful in the preparation of carbapenem antibiotics | Sankyo Company Limited (JP) | 1992-12-02 | — | — | EP | disclosed |