Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910790 | 0.90 | MEN1 (0.44) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7910784 | 0.90 | MEN1 (0.44) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8546202 | 0.88 | MAPK1 (0.44) | KDM4EALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL8549779 | 0.85 | — | — | |
| SCHEMBL8549905 | 0.84 | — | — | |
| SCHEMBL8550515 | 0.81 | — | — | |
| SCHEMBL8551112 | 0.80 | — | — | |
| SCHEMBL8544983 | 0.80 | — | — | |
| SCHEMBL7901079 | 0.79 | GPR132 (0.43) | — | |
| SCHEMBL8544379 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |