Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.71 |
| ▸ | RXRB | P28702 | 15/20 | 0.71 |
| ▸ | RXRG | P48443 | 11/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | C5 | P01031 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314158 | 0.81 | PTGS1 (0.91) | RXRARXRBRXRGPTGS1EPHX2 | |
| SCHEMBL6002180 | 0.80 | NR4A2 (0.62) | RXRARXRBRXRGPTGS1EPHX2 | |
| SCHEMBL6002012 | 0.80 | NR4A2 (0.61) | RXRARXRBRXRGPTGS1EPHX2 | |
| SCHEMBL6002432 | 0.80 | NR4A2 (0.61) | RXRARXRBRXRGPTGS1EPHX2 | |
| SCHEMBL25942096 | 0.78 | NR4A2 (0.66) | RXRARXRBRXRGPTGS1EPHX2 | |
| SCHEMBL21805996 | 0.76 | PTGS1 (1.00) | RXRARXRBRXRGPTGS1EPHX2 | |
| SCHEMBL13014501 | 0.73 | NR4A2 (0.62) | RXRARXRBRXRGPTGS1EPHX2 | |
| SCHEMBL8548372 | 0.73 | RXRA (0.66) | RXRARXRBRXRGPTGS1EPHX2 | |
| SCHEMBL8547260 | 0.72 | PTGS1 (0.70) | RXRARXRBRXRGPTGS1EPHX2 | |
| SCHEMBL17208133 | 0.70 | RXRA (0.72) | RXRARXRBRXRGPTGS1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620501-B1 | Photosensitive composition for volume hologram recording | NIPPON PAINT CO LTD (JP) | 1999-12-01 | — | — | EP | disclosed |
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |