Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908127 | 0.92 | MAOB (0.59) | MAOBNR4A2SMN1; SMN2KMT2ASMPD1 | |
| SCHEMBL8551283 | 0.86 | MAOB (0.55) | MAOBMRGPRX4NR4A2KMT2ASMPD1 | |
| SCHEMBL7901063 | 0.85 | MAOB (0.53) | MAOBMRGPRX4NR4A2SMN1; SMN2KMT2A | |
| SCHEMBL8549883 | 0.85 | MAOB (0.53) | MAOBMRGPRX4NR4A2KMT2ASMPD1 | |
| SCHEMBL7901058 | 0.85 | MAOB (0.53) | MAOBMRGPRX4NR4A2SMN1; SMN2KMT2A | |
| SCHEMBL8550373 | 0.85 | MAOB (0.55) | MAOBMRGPRX4NR4A2SMN1; SMN2KMT2A | |
| SCHEMBL8549981 | 0.84 | MRGPRX4 (0.52) | MAOBMRGPRX4NR4A2SMN1; SMN2SMPD1 | |
| SCHEMBL8546264 | 0.83 | MAOB (0.51) | MAOBMRGPRX4NR4A2SMN1; SMN2KMT2A | |
| SCHEMBL8546324 | 0.82 | PARP14 (0.44) | MAOBNR4A2KMT2AGPR132RAB9A | |
| SCHEMBL8545815 | 0.82 | MAOB (0.54) | MAOBNR4A2KMT2ASMPD1GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |