Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907477 | 0.85 | PARP14 (0.44) | PARP14PARP10GAAHPGDNPC1 | |
| SCHEMBL7907473 | 0.85 | PARP14 (0.44) | PARP14PARP10GAAHPGDNPC1 | |
| SCHEMBL7908127 | 0.85 | MAOB (0.59) | NR4A2MEN1KMT2AMAOBGPR132 | |
| SCHEMBL8546321 | 0.84 | GAA (0.45) | PARP14PARP10GAAHPGDNPC1 | |
| SCHEMBL8546267 | 0.82 | MAOB (0.53) | RAB9ANR4A2KMT2AMAOBGPR132 | |
| SCHEMBL8549883 | 0.82 | MAOB (0.53) | NR4A2KMT2AMAOBGPR132 | |
| SCHEMBL8551283 | 0.79 | MAOB (0.55) | NR4A2MEN1KMT2AMAOBGPR132 | |
| SCHEMBL8550373 | 0.78 | MAOB (0.55) | NR4A2MEN1KMT2AMAOBGPR132 | |
| SCHEMBL8545446 | 0.77 | MAOB (0.46) | HPGDNPC1RAB9AMAOB | |
| SCHEMBL8548526 | 0.76 | MAOB (0.53) | NR4A2MEN1KMT2AMAOBGPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |