Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.51 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543202 | 0.87 | SLC6A2 (0.49) | SLC6A2 | |
| SCHEMBL8539731 | 0.75 | SLC6A2 (0.57) | SLC6A2 | |
| SCHEMBL9739036 | 0.75 | SLC6A2 (0.47) | SLC6A2CCNCCDK8 | |
| SCHEMBL8544345 | 0.74 | SLC6A2 (0.56) | SLC6A2 | |
| SCHEMBL8539804 | 0.71 | SLC6A2 (0.70) | SLC6A2 | |
| Fumaric Acid SCHEMBL7612128 | 0.70 | SLC6A2 (0.79) | SLC6A2CCNCCDK8 | |
| Maleic Acid SCHEMBL7612124 | 0.70 | SLC6A2 (0.79) | SLC6A2CCNCCDK8 | |
| SCHEMBL8544787 | 0.69 | SLC6A2 (0.52) | SLC6A2 | |
| SCHEMBL7610158 | 0.69 | SLC6A2 (1.00) | SLC6A2 | |
| SCHEMBL8541743 | 0.67 | SLC6A2 (0.56) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |