Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14151940 | 0.79 | KDM4E (0.45) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL15544837 | 0.74 | NPC1 (0.44) | TSHRNPC1RAB9A | |
| SCHEMBL31153190 | 0.74 | NPC1 (0.44) | TSHRNPC1RAB9A | |
| SCHEMBL3632915 | 0.74 | KDM4E (0.50) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL27882830 | 0.72 | KDM4E (0.48) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL8543606 | 0.71 | KEAP1 (0.40) | KDM4ETSHRTDP1NPC1RAB9A | |
| SCHEMBL31481077 | 0.69 | KEAP1 (0.45) | KDM4ETSHRNPC1RAB9AKMT2A | |
| SCHEMBL8220478 | 0.69 | SMN1; SMN2 (0.48) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL2595331 | 0.67 | KEAP1 (0.50) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL30012630 | 0.67 | KDM4E (0.46) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434965-B1 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID CO (US) | 1998-05-20 | — | — | EP | disclosed |
| US-5405827-A | 5-heterocyclic 2-(2-imidazolin-2-yl)pyridines, useful as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| US-5344935-A | Intermediates for herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5283230-A | Pre- and post-emergence herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
| US-5239070-A | Herbicide intermediates | AMERICAN CYANAMID COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| US-5225564-A | Acetalization, amination or sulfiding in a solvent | AMERICAN CYANAMID COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5039333-A | 5-heterocyclic 2-(2-imidazolin-2-yl)pyridines, useful as herbicidal agents | AMERICAN CYANAMID COMPANY | 1991-08-13 | — | — | US | disclosed |
| EP-0434965-A2 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5026859-A | Intermediates for herbicides | AMERICAN CYANAMID COMPANY (US) | 1991-06-25 | — | — | US | disclosed |