Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MPL | P40238 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257648 | 0.83 | ALDH1A1 (0.54) | KDM4EMGAMALDH1A1GAASI | |
| SCHEMBL4195782 | 0.81 | HSP90AB1 (0.53) | KDM4EMGAMALDH1A1GAASI | |
| SCHEMBL30256985 | 0.80 | MYC (0.56) | KDM4EALDH1A1RAB9AHSD11B1MPL | |
| SCHEMBL27679618 | 0.78 | HTT (0.66) | KDM4EMGAMALDH1A1GAASI | |
| SCHEMBL954791 | 0.77 | KDM4E (0.48) | KDM4EMGAMALDH1A1GAASI | |
| SCHEMBL1802030 | 0.76 | SMN1; SMN2 (0.65) | KDM4EMGAMALDH1A1GAASI | |
| SCHEMBL954378 | 0.75 | CDC7 (0.68) | KDM4EALDH1A1RAB9AHSP90AB1DPP4 | |
| SCHEMBL4368811 | 0.75 | CDC7 (0.51) | KDM4EMGAMALDH1A1GAASI | |
| SCHEMBL2358704 | 0.74 | MPL (0.54) | ALDH1A1DPP4MPLKMT2ASMN1; SMN2 | |
| SCHEMBL30257362 | 0.74 | MPL (0.54) | ALDH1A1DPP4MPLKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833822-A1 | 4-PHENYLAMINOTHIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000868-A1 | 4-PHENYLAMINOTHIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1997-01-09 | — | — | WO | disclosed |