Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909072 | 0.91 | FFAR1 (0.47) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7909065 | 0.91 | FFAR1 (0.47) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7900943 | 0.84 | MEN1 (0.51) | MEN1KMT2AMAOBFFAR1 | |
| SCHEMBL7900946 | 0.84 | MEN1 (0.51) | MEN1KMT2AMAOBFFAR1 | |
| SCHEMBL8547554 | 0.83 | SMPD1 (0.53) | LMNAMAOBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8546902 | 0.82 | PPARA (0.47) | MEN1KMT2AMAOBRAB9ASMN1; SMN2 | |
| SCHEMBL7907471 | 0.82 | SMPD1 (0.52) | MAOBFFAR1SMPD1 | |
| SCHEMBL7907467 | 0.82 | SMPD1 (0.52) | MAOBFFAR1SMPD1 | |
| SCHEMBL8545508 | 0.81 | MAOB (0.52) | MEN1KMT2AMAOBSMPD1 | |
| SCHEMBL8545812 | 0.80 | MAOB (0.51) | MEN1KMT2AMAOBNR1H4SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |