Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546943 | 0.97 | MAOB (0.51) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL7900813 | 0.87 | NR4A2 (0.55) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL7900814 | 0.87 | NR4A2 (0.55) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL7910935 | 0.84 | NR4A2 (0.56) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL7910937 | 0.84 | NR4A2 (0.56) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL8543419 | 0.82 | MAOB (0.55) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL7900684 | 0.82 | NR4A2 (0.59) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL7900685 | 0.82 | NR4A2 (0.59) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL8546997 | 0.82 | MAOB (0.52) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL21879735 | 0.81 | LMNA (0.55) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |