Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL234 | 1.00 | — | — | |
| Nitric Acid SCHEMBL10981408 | 1.00 | — | — | |
| Nitric Acid SCHEMBL3762342 | 1.00 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL302522 | 1.00 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL7750558 | 1.00 | — | — | |
| Nitric Acid SCHEMBL28411161 | 1.00 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL8383283 | 1.00 | CA5A (1.00) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL37356 | 1.00 | — | — | |
| Nitric Acid SCHEMBL1433664 | 0.94 | — | — | |
| Nitric Acid SCHEMBL21834395 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8020 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036335-B2 | Adhesive containing microparticles | AVERY DENNISON CORPORATION (US) | 2024-07-16 | — | — | US | claimed |
| US-12036222-B2 | Methods of treating cancers overexpressing CARM1 with EZH2 inhibitors and a PARP inhibitor | The Wistar Institut of Anatomy and Biology (US) | 2024-07-16 | — | — | US | claimed |
| WO-2023195805-A9 | ITGB2-MEDIATED DRUG DELIVERY SYSTEM | 트윈피그바이오랩(주) | 2024-07-11 | — | — | WO | claimed |
| US-12030858-B2 | PARP inhibitors for treating cancer and asthma | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | claimed |
| CN-118317951-A | Phthalazine derivatives as pyruvate kinase modulators | 西特瑞治疗有限公司 | 2024-07-09 | — | — | CN | claimed |
| EP-3044190-B1 | BURN RATE MODIFIER | THALES AUSTRALIA LTD (AU) | 2024-07-03 | — | — | EP | claimed |
| US-20240207300-A1 | COMBINATION THERAPIES INCLUDING MYT1 INHIBITORS | SINAI HEALTH SYSTEM (CA) | 2024-06-27 | — | — | US | claimed |
| US-20240207421-A1 | NERVE TARGETING PEPTIDES AND METHODS OF USE | ALUME BIOSCIENCES INC (US) | 2024-06-27 | — | — | US | claimed |
| US-20240197731-A1 | THERAPEUTIC COMPOSITIONS, COMBINATIONS, AND METHODS OF USE | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2024-06-20 | — | — | US | claimed |
| US-20240203601-A1 | ANALYZING COPY NUMBER VARIATION IN THE DETECTION OF CANCER | VERINATA HEALTH, INC. | 2024-06-20 | — | — | US | claimed |
| EP-0043235-B1 | RESIN BONDED WATER BEARING EXPLOSIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-08-07 | — | — | EP | claimed |
| EP-0125166-A1 | Cold-mouldable explosive composition and process for its preparation | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1984-11-14 | — | — | EP | claimed |
| EP-0000523-B1 | FUSE CORD AND PROCESS FOR MAKING IT | ICI AUSTRALIA LIMITED (AU) | 1982-06-16 | — | — | EP | claimed |
| US-4278480-A | Slurry type explosive | JOHANNES GERALD E | 1981-07-14 | — | — | US | claimed |
| US-4132574-A | PENTAERYTHRITOL TETRANITRATE, CROSSLINKING AGENT, GUAR GUM OR POLYACRYLAMIDE, AND AN ALCOHOL OR FORMAMIDE | FORREST CHARLES D | 1979-01-02 | — | — | US | claimed |
| US-4012246-A | PENTAERYTHRITOL TETRANITRATE | TELEDYNE MCCORMICK SELPH, AN OPERATING DIVISION OF TELEDYNE INDUSTRIES, INC. (US) | 1977-03-15 | — | — | US | claimed |
| US-3998597-A | Apparatus for manufacture of sensitized fine particle penetaerythritol tetranitrate | TELEDYNE MCCORMICK SELPH (US) | 1976-12-21 | — | — | US | claimed |
| US-3977922-A | NITRO COMPOUNDS IN THERMOSETTING RESINS | NIPPON OILS AND FATS COMPANY LIMITED (JA) | 1976-08-31 | — | — | US | claimed |
| US-3964392-A | Land mine (U) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1976-06-22 | — | — | US | claimed |
| US-3957550-A | EXPLOSIVES, LIQUID FUELS, OXIDIZERS | THIOKOL CORPORATION (US) | 1976-05-18 | — | — | US | claimed |