Nitric Acid

Nitric Acid

SCHEMBL8547

O=[N+]([O-])O.O=[N+]([O-])O.O=[N+]([O-])O.O=[N+]([O-])O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ERG11

The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 1.00
CA5B Q9Y2D0 1/20 1.00
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 4/20 0.39
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
HIF1A Q16665 2/20 0.36
HPGD P15428 1/20 0.36
LMNA P02545 2/20 0.32
BLM P54132 1/20 0.32
HBB P68871 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitric Acid SCHEMBL234 1.00
Nitric Acid SCHEMBL8383283 1.00 CA5A (1.00) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL302522 1.00 CA5A (1.00) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL37356 1.00
Nitric Acid SCHEMBL3762342 1.00 CA5A (1.00) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL28411161 1.00 CA5A (1.00) CA5ACA5BMEN1KMT2AALDH1A1
Nitric Acid SCHEMBL7750558 1.00
Nitric Acid SCHEMBL10981408 1.00
Nitric Acid SCHEMBL7876245 0.94
Nitric Acid SCHEMBL21834395 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8020 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036335-B2 Adhesive containing microparticles AVERY DENNISON CORPORATION (US) 2024-07-16 US claimed
US-12036222-B2 Methods of treating cancers overexpressing CARM1 with EZH2 inhibitors and a PARP inhibitor The Wistar Institut of Anatomy and Biology (US) 2024-07-16 US claimed
WO-2023195805-A9 ITGB2-MEDIATED DRUG DELIVERY SYSTEM 트윈피그바이오랩(주) 2024-07-11 WO claimed
US-12030858-B2 PARP inhibitors for treating cancer and asthma OREGON HEALTH & SCIENCE UNIVERSITY (US) 2024-07-09 US claimed
CN-118317951-A Phthalazine derivatives as pyruvate kinase modulators 西特瑞治疗有限公司 2024-07-09 CN claimed
EP-3044190-B1 BURN RATE MODIFIER THALES AUSTRALIA LTD (AU) 2024-07-03 EP claimed
US-20240207300-A1 COMBINATION THERAPIES INCLUDING MYT1 INHIBITORS SINAI HEALTH SYSTEM (CA) 2024-06-27 US claimed
US-20240207421-A1 NERVE TARGETING PEPTIDES AND METHODS OF USE ALUME BIOSCIENCES INC (US) 2024-06-27 US claimed
US-20240197731-A1 THERAPEUTIC COMPOSITIONS, COMBINATIONS, AND METHODS OF USE THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2024-06-20 US claimed
US-20240203601-A1 ANALYZING COPY NUMBER VARIATION IN THE DETECTION OF CANCER VERINATA HEALTH, INC. 2024-06-20 US claimed
EP-0043235-B1 RESIN BONDED WATER BEARING EXPLOSIVE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-07 EP claimed
EP-0125166-A1 Cold-mouldable explosive composition and process for its preparation COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1984-11-14 EP claimed
EP-0000523-B1 FUSE CORD AND PROCESS FOR MAKING IT ICI AUSTRALIA LIMITED (AU) 1982-06-16 EP claimed
US-4278480-A Slurry type explosive JOHANNES GERALD E 1981-07-14 US claimed
US-4132574-A PENTAERYTHRITOL TETRANITRATE, CROSSLINKING AGENT, GUAR GUM OR POLYACRYLAMIDE, AND AN ALCOHOL OR FORMAMIDE FORREST CHARLES D 1979-01-02 US claimed
US-4012246-A PENTAERYTHRITOL TETRANITRATE TELEDYNE MCCORMICK SELPH, AN OPERATING DIVISION OF TELEDYNE INDUSTRIES, INC. (US) 1977-03-15 US claimed
US-3998597-A Apparatus for manufacture of sensitized fine particle penetaerythritol tetranitrate TELEDYNE MCCORMICK SELPH (US) 1976-12-21 US claimed
US-3977922-A NITRO COMPOUNDS IN THERMOSETTING RESINS NIPPON OILS AND FATS COMPANY LIMITED (JA) 1976-08-31 US claimed
US-3964392-A Land mine (U) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-06-22 US claimed
US-3957550-A EXPLOSIVES, LIQUID FUELS, OXIDIZERS THIOKOL CORPORATION (US) 1976-05-18 US claimed