Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 2/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27297444 | 0.95 | RAB9A (0.67) | RAB9ATSHRNPC1L3MBTL1CYP1A2 | |
| SCHEMBL8548739 | 0.90 | RAB9A (0.69) | RAB9ATSHRNPC1L3MBTL1CYP1A2 | |
| SCHEMBL8547053 | 0.85 | RAB9A (0.51) | RAB9ATSHRNPC1L3MBTL1CYP1A2 | |
| SCHEMBL8543918 | 0.85 | RAB9A (0.51) | RAB9ATSHRNPC1L3MBTL1CYP1A2 | |
| SCHEMBL1630083 | 0.84 | RAB9A (0.54) | RAB9ATSHRNPC1L3MBTL1CYP1A2 | |
| SCHEMBL8540692 | 0.84 | RAB9A (0.65) | RAB9ATSHRNPC1L3MBTL1CYP1A2 | |
| SCHEMBL1627176 | 0.84 | RAB9A (0.54) | RAB9ATSHRNPC1L3MBTL1CYP1A2 | |
| SCHEMBL11938506 | 0.84 | RAB9A (0.54) | RAB9ATSHRNPC1L3MBTL1CYP1A2 | |
| SCHEMBL8542382 | 0.84 | RAB9A (0.56) | RAB9ATSHRNPC1L3MBTL1CYP1A2 | |
| SCHEMBL28731954 | 0.83 | RAB9A (0.62) | RAB9ATSHRNPC1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | disclosed |
| CN-1035825-A | Quinazoline derivant | LILLY CO ELI (US) | 1989-09-27 | — | — | CN | disclosed |