Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11053215 | 0.81 | CA2 (0.61) | CA2CA9CA1KMT2ATSHR | |
| SCHEMBL2687935 | 0.80 | CA1 (0.43) | CA2CA9CA1CA12 | |
| SCHEMBL4334012 | 0.79 | CA2 (0.43) | CA2CA9CA1KMT2ATSHR | |
| SCHEMBL6212916 | 0.78 | CA2 (0.52) | CA2CA9CA1KMT2A | |
| SCHEMBL332355 | 0.78 | CA2 (0.63) | CA2CA9CA1KMT2ATSHR | |
| Ammonia Solution, Strong SCHEMBL28824538 | 0.77 | CA2 (0.61) | CA2CA9CA1KMT2ATSHR | |
| Ammonia Solution, Strong SCHEMBL28824537 | 0.77 | CA2 (0.61) | CA2CA9CA1KMT2ATSHR | |
| SCHEMBL6429397 | 0.77 | CA2 (0.50) | CA2CA9CA1KMT2ATSHR | |
| Hydrogen Sulfide SCHEMBL12483354 | 0.77 | CA2 (0.61) | CA2CA9CA1KMT2ATSHR | |
| Ammonia Solution, Strong SCHEMBL27830775 | 0.77 | CA2 (0.61) | CA2CA9CA1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659747-B1 | Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1998-04-01 | — | — | EP | claimed |
| US-5821255-A | REGULATING THE SECRETION OF CORTICOTROPIN, BETA-ENDORPHIN OR PEPTIDES DERIVED FROM PROOPIOMELANOCORTIN | SANOFI (FR) | 1998-10-13 | — | — | US | disclosed |
| EP-0659747-B1 | Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1998-04-01 | — | — | EP | disclosed |
| US-5602132-A | USEFUL IN TREATMENT OF PATHOLOGIES INVOLVING CORTICOTROPIN RELEASING FACTOR | SANOFI (FR) | 1997-02-11 | — | — | US | disclosed |
| EP-0659747-A1 | Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1995-06-28 | — | — | EP | disclosed |