Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTPRF | P10586 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302942 | 0.80 | PTPN1 (0.69) | TSHRPTPN1PTPN2PTPN6PTPN11 | |
| SCHEMBL10092005 | 0.78 | CHRNA7 (0.48) | TSHRALDH1A1KDM4EPOLBHSD17B10 | |
| SCHEMBL29804712 | 0.78 | CHRNA7 (0.54) | TSHRALDH1A1KDM4EPOLBHSD17B10 | |
| SCHEMBL8837628 | 0.76 | ALDH1A1 (0.60) | TSHRALDH1A1KDM4EPOLBHSD17B10 | |
| SCHEMBL1786140 | 0.74 | MEN1 (0.69) | TSHRPOLBCHRNA7MEN1KMT2A | |
| SCHEMBL4453290 | 0.74 | MEN1 (0.69) | TSHRPOLBCHRNA7MEN1KMT2A | |
| SCHEMBL9706667 | 0.74 | ALDH1A1 (0.57) | TSHRALDH1A1KDM4EPOLBHSD17B10 | |
| SCHEMBL9248196 | 0.71 | MEN1 (0.65) | POLBCHRNA7MEN1KMT2AGAA | |
| SCHEMBL1926317 | 0.71 | MEN1 (0.65) | POLBCHRNA7MEN1KMT2AGAA | |
| Methyl Benzoate SCHEMBL10807981 | 0.71 | TSHR (0.76) | TSHRALDH1A1POLBPTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840734-A1 | SUBSTITUTED ARYL SULPHONYL AMINO (THIO) CARBONYL TRIAZOLIN(THI)ONES | BAYER AG (DE) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997003980-A1 | SUBSTITUTED ARYL SULPHONYL AMINO (THIO) CARBONYL TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-06 | — | — | WO | disclosed |