Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.37 |
| ▸ | CIT | O14578 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548225 | 1.00 | DPP4 (0.41) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL12234222 | 1.00 | DPP4 (0.41) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL22369892 | 1.00 | DPP4 (0.41) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL27510062 | 0.85 | PIK3CD (0.43) | DPP4DPP8DPP9TERTDPP7 | |
| SCHEMBL3149344 | 0.85 | PIK3CD (0.43) | DPP4DPP8DPP9TERTDPP7 | |
| SCHEMBL29858297 | 0.83 | KDM4C (0.41) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL22369849 | 0.82 | POLB (0.34) | DPP4 | |
| SCHEMBL3258317 | 0.80 | POLB (0.39) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL24543397 | 0.79 | POLB (0.40) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL24543161 | 0.79 | POLB (0.40) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670675-B1 | AN AQUEOUS ALKALINE METAL WORKING FLUID CONTAINING A PRIMARY AMINE | BEROL NOBEL AB (SE) | 1999-03-24 | — | — | EP | disclosed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5633222-A | SUCH AS METAL WORKING FLUIDS | BEROL NOBEL AB (SE) | 1997-05-27 | — | — | US | disclosed |
| EP-0674696-A1 | USE OF A SECONDARY AMINE AS A CORROSION INHIBITING AND ANTIMICROBIAL AGENT AND AN AQUEOUS ALKALINE INDUSTRIAL FLUID CONTAINING SAID AMINE | BEROL NOBEL AB (SE) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994013765-A1 | USE OF A SECONDARY AMINE AS A CORROSION INHIBITING AND ANTIMICROBIAL AGENT AND AN AQUEOUS ALKALINE INDUSTRIAL FLUID CONTAINING SAID AMINE | BEROL NOBEL AB (SE) | 1994-06-23 | — | — | WO | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |
| EP-0386611-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-09-12 | — | — | EP | disclosed |