Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355353 | 0.87 | DPP4 (0.47) | POLBEPHX1MEN1KMT2AALDH1A1 | |
| SCHEMBL12234234 | 0.87 | POLB (0.40) | POLBEPHX1ALDH1A1DPP4FAP | |
| SCHEMBL24543397 | 0.87 | POLB (0.40) | POLBEPHX1ALDH1A1DPP4FAP | |
| SCHEMBL24543396 | 0.87 | POLB (0.40) | POLBEPHX1ALDH1A1DPP4FAP | |
| SCHEMBL10451323 | 0.87 | DPP4 (0.47) | POLBEPHX1MEN1KMT2AALDH1A1 | |
| SCHEMBL24543161 | 0.87 | POLB (0.40) | POLBEPHX1ALDH1A1DPP4FAP | |
| SCHEMBL23975825 | 0.87 | DPP4 (0.47) | POLBEPHX1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL356236 | 0.85 | DPP4 (0.45) | POLBEPHX1ALDH1A1DPP4FAP | |
| SCHEMBL12234218 | 0.81 | DPP4 (0.43) | POLBEPHX1MEN1KMT2AALDH1A1 | |
| SCHEMBL24543407 | 0.81 | DPP4 (0.43) | POLBEPHX1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099749-B1 | C-H BOND AMINATION AND OLEFIN AZIRIDINATION WITH BETA-DIKETIMINATO COPPER CATALYSTS | UNIV GEORGETOWN (US) | 2015-09-23 | — | — | EP | disclosed |
| US-8471051-B2 | C-H bond amination and olefin aziridination with β-diketiminato copper catalysts | GEORGETOWN UNIVERSITY (US) | 2013-06-25 | — | — | US | disclosed |
| US-20100056806-A1 | C-H Bond Amination and Olefin Aziridination with Beta-Diketiminato Copper Catalysts | GEORGETOWN UNIVERSITY (US) | 2010-03-04 | — | — | US | disclosed |
| EP-2099749-A2 | C--H BOND AMINATION AND OLEFIN AZIRIDINATION WITH BETA-DIKETIMINATO COPPER CATALYSTS | Georgetown University (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008073781-A2 | C--H BOND AMINATION AND OLEFIN AZIRIDINATION WITH BETA-DIKETIMINATO COPPER CATALYSTS | GEORGETOWN UNIVERSITY (US) | 2008-06-19 | — | — | WO | disclosed |
| WO-2005007659-A2 | DIKETIMINATO CU(I) AND CO(I) CARBENE CATALYSTS, AND CYCLOPROPANATION METHODS USING THEM | GEORGETOWN UNIVERSITY (US) | 2005-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056806-A1 | C-H Bond Amination and Olefin Aziridination with Beta-Diketiminato Copper Catalysts | AOC2, AOC1, AOC3 | POLB 932/4885EPHX1 969/4885MEN1 4687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.