Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503288 | 0.86 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL2992927 | 0.85 | MAPT (0.37) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2989585 | 0.84 | ALDH1A1 (0.35) | ALDH1A1LMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL2987015 | 0.83 | CYP2C9 (0.40) | — | |
| SCHEMBL2983769 | 0.82 | MAPT (0.36) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL6839830 | 0.81 | TDP1 (0.44) | MAPK14ALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL2984245 | 0.81 | MEN1 (0.38) | LMNAMAPTNPSR1 | |
| SCHEMBL2990341 | 0.81 | MEN1 (0.38) | LMNAMAPTNPSR1 | |
| SCHEMBL2985373 | 0.81 | MEN1 (0.38) | LMNAMAPTNPSR1 | |
| SCHEMBL2992892 | 0.81 | MEN1 (0.38) | LMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0295603-B1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | EISAI CO LTD (JP) | 1996-09-18 | — | — | EP | disclosed |
| EP-0295603-A1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | Eisai Co., Ltd. (JP) | 1988-12-21 | — | — | EP | disclosed |