Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | WDR5 | P61964 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.47 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | NPY1R | P25929 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.47 |
| ▸ | FASN | P49327 | 2/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500260 | 0.92 | KMT2A (0.47) | CYP2C9WDR5KMT2AENGASEDDAH1 | |
| SCHEMBL23988383 | 0.90 | KMT2A (0.46) | CYP2C9WDR5KMT2AENGASEDDAH1 | |
| SCHEMBL13285144 | 0.90 | CYP2C9 (0.46) | CYP2C9WDR5KMT2AENGASEDDAH1 | |
| SCHEMBL23988394 | 0.90 | KMT2A (0.46) | CYP2C9WDR5KMT2AENGASEDDAH1 | |
| SCHEMBL8548480 | 0.90 | CYP2C9 (0.46) | CYP2C9WDR5KMT2AENGASEDDAH1 | |
| SCHEMBL8503315 | 0.90 | KMT2A (0.46) | CYP2C9WDR5KMT2AENGASEDDAH1 | |
| Rabeprazole SCHEMBL6081725 | 0.89 | KMT2A (0.60) | CYP2C9WDR5KMT2AENGASEDDAH1 | |
| Rabeprazole SCHEMBL6081727 | 0.89 | KMT2A (0.60) | CYP2C9WDR5KMT2AENGASEDDAH1 | |
| SCHEMBL8503340 | 0.89 | CYP2C9 (0.46) | CYP2C9WDR5KMT2AENGASEDDAH1 | |
| Dexrabeprazole SCHEMBL4946138 | 0.88 | KMT2A (0.61) | CYP2C9WDR5KMT2AENGASEDDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070942-A1 | PRAZOLE DERIVATIVES AND SALTS THEREOF AND USE OF SAME | JIANGSU HANSEN PHARMACEUTICAL CO., LTD. (CN) | 2008-03-20 | — | — | US | disclosed |
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0268956-B2 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | EISAI CO LTD (JP) | 1998-04-15 | — | — | EP | disclosed |
| EP-0786461-A1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1997-07-30 | — | — | EP | disclosed |
| EP-0654471-A1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and process for preparing the same | Eisai Co., Ltd. (JP) | 1995-05-24 | — | — | EP | disclosed |
| EP-0475456-A1 | Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same | Eisai Co., Ltd. (JP) | 1992-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070942-A1 | PRAZOLE DERIVATIVES AND SALTS THEREOF AND USE OF SAME | SLC10A2, GIPR, CACNA1E | CYP2C9 96/4885WDR5 2930/4885KMT2A 2743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.