Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182063 | 0.87 | CA2 (0.45) | CA2SMN1; SMN2KDM4EALDH1A1TYR | |
| SCHEMBL27693512 | 0.83 | CA2 (0.45) | CA2SMN1; SMN2KDM4EALDH1A1TYR | |
| SCHEMBL1807380 | 0.83 | KDM4E (0.46) | CA2KDM4EALDH1A1PDIA6POLB | |
| SCHEMBL1807383 | 0.81 | KDM4E (0.44) | CA2KDM4EALDH1A1PDIA6POLB | |
| SCHEMBL28906315 | 0.81 | CA2 (0.45) | CA2SMN1; SMN2KDM4EALDH1A1TYR | |
| SCHEMBL28906302 | 0.81 | CA2 (0.45) | CA2SMN1; SMN2KDM4EALDH1A1TYR | |
| SCHEMBL12497682 | 0.81 | CA2 (0.45) | CA2SMN1; SMN2KDM4EALDH1A1TYR | |
| SCHEMBL28605818 | 0.81 | CA2 (0.45) | CA2SMN1; SMN2KDM4EALDH1A1TYR | |
| SCHEMBL1802835 | 0.79 | KDM4E (0.48) | CA2KDM4EALDH1A1PDIA6POLB | |
| SCHEMBL30892432 | 0.79 | CA2 (0.46) | CA2SMN1; SMN2KDM4EALDH1A1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |