Oxirane

Oxirane

SCHEMBL8548329

C1CO1.C=CCc1ccccc1OP(=O)(O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 4/20 0.46
ADRB1 P08588 4/20 0.46
ADRB3 P13945 2/20 0.46
SRC P12931 1/20 0.44
INPPL1 O15357 1/20 0.41
INPP5B P32019 1/20 0.41
INPP5A Q14642 1/20 0.41
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 4/20 0.41
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41
PDE3A Q14432 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTR1A P08908 2/20 0.39
ADRA2C P18825 2/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
LMNA P02545 1/20 0.39
SLC6A2 P23975 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175488 0.92 SRC (0.50) ADRB2ADRB1ADRB3SRCINPPL1
Ether SCHEMBL4078185 0.84 ALDH1A1 (0.45) ADRB2ADRB1ADRB3SRCINPPL1
Ether SCHEMBL23302569 0.83 ALDH1A1 (0.44) ADRB2ADRB1ADRB3SRCINPPL1
SCHEMBL3474948 0.83 KDM4E (0.45) ADRB2ADRB1ADRB3KDM4EALDH1A1
Trolamine SCHEMBL762060 0.82 SRC (0.41) ADRB2ADRB1ADRB3SRCINPPL1
SCHEMBL5612242 0.81 KDM4E (0.41) ADRB2ADRB1ADRB3SRCKDM4E
SCHEMBL778135 0.80 KDM4E (0.43) ADRB2ADRB1ADRB3KDM4EALDH1A1
SCHEMBL779407 0.80 KDM4E (0.46) ADRB2ADRB1ADRB3KDM4EALDH1A1
SCHEMBL31127744 0.79 KDM4E (0.44) ADRB2ADRB1ADRB3KDM4EALDH1A1
SCHEMBL541751 0.79 KDM4E (0.44) ADRB2ADRB1ADRB3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922789-A A MIXTURE OF GELATIN AND A COPOLYMER OF ETHYLENICALLY UNSATURATED MONOMERS AND EMULSIFER WITH IONIC OR NONIONIC GROUPS; USEFUL FOR PREPARING PHOTOGRAPHIC PAPERS, FILMS AND INKJET RECORDING MATERIALS WACKER-CHEMIE GMBH (DE) 1999-07-13 US disclosed