Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542966 | 1.00 | FFAR3 (0.39) | FFAR3ALDH1A1ALOX15MAPK1TP53 | |
| SCHEMBL8542970 | 1.00 | FFAR3 (0.39) | FFAR3ALDH1A1ALOX15MAPK1TP53 | |
| SCHEMBL18220609 | 0.78 | — | — | |
| SCHEMBL7265168 | 0.76 | FFAR3 (0.38) | FFAR3MAPK1TP53NFKB1CYP2C19 | |
| SCHEMBL27982894 | 0.74 | — | — | |
| SCHEMBL22068717 | 0.74 | FFAR3 (0.36) | FFAR3ALDH1A1 | |
| SCHEMBL2505352 | 0.72 | FFAR3 (0.36) | FFAR3 | |
| SCHEMBL8189806 | 0.71 | FFAR3 (0.30) | FFAR3 | |
| SCHEMBL13818283 | 0.70 | ALDH1A1 (0.34) | FFAR3ALDH1A1ALOX15TP53 | |
| SCHEMBL19307390 | 0.69 | FFAR3 (0.47) | FFAR3ALDH1A1MAPK1TP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886635-A1 | 2-AMINO-5,6-DICHLOROBENZIMIDAZOLE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | GLAXO GROUP LIMITED (GB) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997025316-A1 | 2-AMINO-5,6-DICHLOROBENZIMIDAZOLE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | GLAXO GROUP LIMITED (GB) | 1997-07-17 | — | — | WO | disclosed |