Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523605 | 0.79 | MAPK1 (0.56) | MAPK1HTTTSHRRECQLESR1 | |
| SCHEMBL20777186 | 0.78 | SMN1; SMN2 (0.50) | HTTTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9725344 | 0.77 | MAPK1 (0.50) | MAPK1HTTTSHRRECQLESR1 | |
| SCHEMBL6770806 | 0.73 | NPC1 (0.52) | MAPK1HTTTSHRRECQLMEN1 | |
| SCHEMBL13053067 | 0.73 | MAPK1 (0.61) | MAPK1HTTTSHRRECQLESR1 | |
| SCHEMBL6772044 | 0.72 | ADORA3 (0.34) | MAPK1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL31702451 | 0.71 | CYP1A2 (0.39) | MAPK1HTTTSHRRECQLMEN1 | |
| SCHEMBL13750288 | 0.71 | MAPK1 (0.63) | MAPK1HTTTSHRRECQLESR1 | |
| SCHEMBL15835577 | 0.69 | MAPK1 (0.61) | MAPK1HTTTSHRRECQLESR1 | |
| SCHEMBL2309144 | 0.69 | MAPK1 (0.61) | MAPK1HTTTSHRRECQLESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846689-A1 | Benzimidazole compounds | PFIZER INC. (US) | 1998-06-10 | — | — | EP | disclosed |