Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 13/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357715 | 0.94 | LMNA (0.52) | MAPTKMT2AMEN1NPC1CTSD | |
| SCHEMBL8358172 | 0.88 | LMNA (0.59) | MAPTKMT2AMEN1NPC1CTSD | |
| SCHEMBL8361572 | 0.85 | KMT2A (0.50) | MAPTKMT2AMEN1NPC1CTSD | |
| SCHEMBL8361573 | 0.83 | LMNA (0.53) | MAPTKMT2AMEN1NPC1CTSD | |
| SCHEMBL8361495 | 0.83 | LMNA (0.53) | MAPTKMT2AMEN1NPC1CTSD | |
| SCHEMBL8356666 | 0.83 | KMT2A (0.48) | MAPTKMT2AMEN1NPC1CTSD | |
| SCHEMBL8357707 | 0.81 | MAPT (0.51) | MAPTKMT2AMEN1NPC1CTSD | |
| SCHEMBL8356256 | 0.80 | KMT2A (0.65) | MAPTKMT2AMEN1NPC1CTSD | |
| SCHEMBL8359497 | 0.80 | MAPT (0.48) | MAPTKMT2AMEN1NPC1CTSD | |
| SCHEMBL8357950 | 0.79 | LMNA (0.60) | MAPTKMT2AMEN1NPC1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824529-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035681-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-11-14 | — | — | WO | disclosed |