Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548754 | 0.92 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL8548829 | 0.90 | AGTR1 (0.60) | AGTR1 | |
| SCHEMBL8544373 | 0.90 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL8548786 | 0.88 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL6568027 | 0.88 | AGTR1 (0.63) | AGTR1 | |
| SCHEMBL8548732 | 0.85 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL8548750 | 0.84 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL8548712 | 0.84 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL8548853 | 0.82 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL8550698 | 0.82 | AGTR1 (0.43) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514198-B1 | 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group | GLAXO GROUP LTD (GB) | 1998-08-05 | — | — | EP | claimed |