Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.62 |
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498791 | 0.83 | PRCP (0.68) | PRCPNOS2HTR2CHTR2BTLR2 | |
| SCHEMBL8548319 | 0.83 | PRCP (0.68) | PRCPNOS2HTR2CHTR2BTLR2 | |
| SCHEMBL15329272 | 0.82 | PRCP (0.70) | PRCPNOS2HTR2CHTR2BTLR2 | |
| SCHEMBL29808626 | 0.82 | PRCP (0.46) | PRCPNOS2NOS3NOS1HTR2C | |
| SCHEMBL6478315 | 0.81 | PRCP (0.69) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL21585404 | 0.81 | PRCP (0.69) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL6485869 | 0.81 | PRCP (0.69) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL17711236 | 0.81 | MEN1 (0.47) | PRCPNOS2NOS3NOS1DPP7 | |
| SCHEMBL8759336 | 0.81 | MEN1 (0.47) | PRCPNOS2NOS3NOS1DPP7 | |
| SCHEMBL31487414 | 0.81 | MEN1 (0.47) | PRCPNOS2NOS3NOS1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874841-A1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR B2 ANTAGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024349-A1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR ANTAGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-07-10 | — | — | WO | disclosed |