Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.69 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21585404 | 1.00 | PRCP (0.69) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL6478315 | 1.00 | PRCP (0.69) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL23762353 | 0.95 | PRCP (0.72) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL21582234 | 0.89 | PRCP (0.64) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL5735106 | 0.89 | PRCP (0.64) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL4578350 | 0.89 | PRCP (0.64) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL13165149 | 0.89 | PRCP (0.57) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL15329272 | 0.87 | PRCP (0.70) | PRCPHTR2CHTR2BTLR2DPP7 | |
| SCHEMBL8548319 | 0.85 | PRCP (0.68) | PRCPHTR2CHTR2BTLR2DPP7 | |
| Oxalic Acid SCHEMBL9348834 | 0.85 | PRCP (0.59) | PRCPHTR2CHTR2BTLR2DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230001399-A1 | NEW TRANSITION METAL CATALYST | DSM IP ASSETS B.V. (NL) | 2023-01-05 | — | — | US | disclosed |
| EP-3819295-A1 | STEREOSELECTIVE SYNTHESIS OF ENANTIOMERICALLY-ENRICHED PANTOLACTONE | DSM IP Assets B.V. (NL) | 2021-05-12 | — | — | EP | disclosed |
| WO-2019228874-A1 | STEREOSELECTIVE SYNTHESIS OF ENANTIOMERICALLY-ENRICHED PANTOLACTONE | DSM IP ASSETS B.V. (NL) | 2019-12-05 | — | — | WO | disclosed |
| US-6897210-B2 | Quinazoline derivatives and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 2005-05-24 | — | — | US | disclosed |
| US-20040242574-A1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZENECA LIMITED | 2004-12-02 | — | — | US | disclosed |
| EP-0929530-A1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZENECA LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013354-A1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZENECA LIMITED (GB) | 1998-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242574-A1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CNKSR1, FLT1, NR5A1 | PRCP 3603/4885HTR2C 552/4885HTR2B 1625/4885 |
| US-20230001399-A1 | NEW TRANSITION METAL CATALYST | SOD1, FECH, SPR | PRCP 1800/4885HTR2C 4559/4885HTR2B 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.