Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GLB1 | P16278 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115135 | 0.79 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL289406 | 0.76 | CRBN (0.41) | ALDH1A1CRBNPRKCAHTTLMNA | |
| SCHEMBL4461377 | 0.75 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL28660448 | 0.73 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL28660449 | 0.73 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL6439316 | 0.72 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CRBNMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7283914 | 0.72 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL7119012 | 0.69 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7944928 | 0.68 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7622428 | 0.68 | MEN1 (0.34) | ALDH1A1L3MBTL1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824523-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. Searle & Co. (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035677-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. SEARLE & CO. (US) | 1996-11-14 | — | — | WO | disclosed |