Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854560 | 0.83 | SYK (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL856315 | 0.81 | NOTUM (0.36) | NPC1RAB9ASMN1; SMN2KITL3MBTL1 | |
| SCHEMBL855418 | 0.80 | NOTUM (0.36) | NPC1RAB9ASMN1; SMN2KITL3MBTL1 | |
| SCHEMBL855480 | 0.73 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL854507 | 0.72 | NOTUM (0.35) | KIT | |
| SCHEMBL855170 | 0.72 | PDE3B (0.31) | — | |
| SCHEMBL854921 | 0.72 | PTGS2 (0.30) | PTGS2 | |
| SCHEMBL854624 | 0.71 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL854959 | 0.70 | NOTUM (0.35) | NPC1RAB9ASMN1; SMN2KITL3MBTL1 | |
| SCHEMBL855479 | 0.70 | NOTUM (0.37) | NPC1RAB9ASMN1; SMN2KITL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432762-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |