SCHEMBL8548952

SCHEMBL8548952

CC(C)(C)c1cc(C(C)(C)C)c(O)c(C(C)(C)c2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.58
CA1 P00915 2/20 0.58
ALDH1A1 P00352 5/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
POLB P06746 1/20 0.56
TYR P14679 1/20 0.56
ALOX15 P16050 3/20 0.50
MAPT P10636 2/20 0.50
HPN P05981 1/20 0.50
SIRT5 Q9NXA8 1/20 0.50
HSP90AA1 P07900 1/20 0.49
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
NR5A2 O00482 1/20 0.46
NR5A1 Q13285 1/20 0.46
CYP1A2 P05177 4/20 0.46
TSHR P16473 3/20 0.46
CYP2C9 P11712 3/20 0.46
CYP2C19 P33261 3/20 0.46
CYP3A4 P08684 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35141 0.93 CA2 (0.67) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL8986512 0.88 CA2 (0.61) CA2CA1ALDH1A1SMN1; SMN2POLB
Trimethylammonium SCHEMBL29145211 0.86 CA2 (0.58) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL39689 0.85 CA2 (0.64) CA2CA1ALDH1A1SMN1; SMN2POLB
Butylated Hydroxytoluene SCHEMBL8034258 0.84 CA2 (0.82) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL10880177 0.84 CYP2C19 (0.54) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL10746183 0.82 CA2 (0.54) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL9861329 0.82 CA2 (0.54) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL247483 0.81 CA2 (0.52) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL29671062 0.81 HSP90AA1 (0.62) CA2CA1ALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110168065-A Low viscosity lubricating oil composition for turbomachinery 埃克森美孚研究工程公司 2019-08-23 CN disclosed
CN-110099948-A Polyetherimide powder for increasing material manufacturing 沙特基础工业全球技术有限公司 2019-08-06 CN disclosed
CN-110023455-A The liquid crystal film of polymerisable liquid crystal material and polymerization 默克专利股份有限公司 2019-07-16 CN disclosed
CN-110023456-A Polymerizable LC medium and the polymer film with planar wave dispersion 默克专利股份有限公司 2019-07-16 CN disclosed
CN-109790465-A The liquid crystal film of polymerisable liquid crystal material and polymerization 默克专利股份有限公司 2019-05-21 CN disclosed
CN-105399730-B Sterically hindered amine stabilizer 巴斯夫欧洲公司 2019-02-22 CN disclosed
CN-105754099-B Composition and polymer 旭化成株式会社 2018-09-18 CN disclosed
CN-104955926-B For improving the lubricant compositions for including epoxide compound of fluoropolymer sealant compatibility 巴斯夫欧洲公司 2018-06-22 CN disclosed
CN-103459569-B Lubricant compositions with improved non-Newtonian viscosity behavior 巴斯夫欧洲公司 2018-01-19 CN disclosed
CN-104271654-B polyamide composition with improved optical properties 巴斯夫欧洲公司 2016-10-19 CN disclosed
CN-103502342-A 5H-furan-2-one derivatives for stabilization of organic material BASF SE 2014-01-08 CN disclosed
CN-103502315-A Composition and polymer ASAHI KASEI CHEMICALS CORP 2014-01-08 CN disclosed
CN-103502343-A Additives for high-flow polymers BASF SE 2014-01-08 CN disclosed
CN-103442567-A Compositions containing polymeric, ionic compounds comprising imidazolium groups BASF SE 2013-12-11 CN disclosed
CN-102137889-B Stabilisers for inanimate organic materials BASF SE 2013-11-13 CN disclosed
CN-101472998-B Reversibly thermochromic compositions CIBA HOLDING INC 2013-06-12 CN disclosed
CN-101796119-B Stabilizer mixture BASF SE 2013-06-12 CN disclosed
EP-0662101-B1 PROCESS FOR STABILISING RECYCLED PLASTICS CIBA HOLDING INC (CH) 2009-05-06 EP disclosed
EP-0754723-B1 Synergistic stabiliser mixture CIBA GEIGY AG (CH) 1999-04-28 EP disclosed
US-3940365-A PHENOLIC ANTIOXIDANT AND AN UREA OR AN OXALIC ACID DIAMIDE OR AN AZODICARBOXYLIC AMIDE HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-24 US disclosed