Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | PRCP | P42785 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | MMP8 | P22894 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MMP14 | P50281 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550314 | 1.00 | MEN1 (0.67) | MEN1KMT2APOLBCTDSP1PRCP | |
| SCHEMBL8549167 | 1.00 | MEN1 (0.67) | MEN1KMT2APOLBCTDSP1PRCP | |
| SCHEMBL7316186 | 0.88 | MEN1 (0.56) | MEN1KMT2APOLBPRCPKDM4E | |
| SCHEMBL7314845 | 0.88 | MEN1 (0.56) | MEN1KMT2APOLBPRCPKDM4E | |
| SCHEMBL8615988 | 0.88 | MEN1 (0.56) | MEN1KMT2APOLBPRCPKDM4E | |
| SCHEMBL7314855 | 0.88 | MEN1 (0.56) | MEN1KMT2APOLBPRCPKDM4E | |
| Hydrochloric Acid SCHEMBL8614876 | 0.86 | MEN1 (0.54) | MEN1KMT2APOLBPRCPKDM4E | |
| Hydrochloric Acid SCHEMBL8614868 | 0.86 | MEN1 (0.54) | MEN1KMT2APOLBPRCPKDM4E | |
| SCHEMBL7315854 | 0.83 | MEN1 (0.60) | MEN1KMT2APOLBCTDSP1PRCP | |
| SCHEMBL13479489 | 0.83 | MEN1 (0.60) | MEN1KMT2APOLBCTDSP1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |