Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316186 | 1.00 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL8615988 | 1.00 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL7314845 | 1.00 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| Hydrochloric Acid SCHEMBL8614868 | 0.98 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| Hydrochloric Acid SCHEMBL8614876 | 0.98 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL8549172 | 0.88 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2PRCPKDM4E | |
| SCHEMBL8549167 | 0.88 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2PRCPKDM4E | |
| SCHEMBL8550314 | 0.88 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2PRCPKDM4E | |
| SCHEMBL7318689 | 0.83 | LMNA (0.51) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL7311069 | 0.83 | LMNA (0.51) | MEN1KMT2ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |