Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543419 | 0.93 | MAOB (0.55) | NR4A2MAOBMEN1KMT2ASMPD1 | |
| SCHEMBL8546084 | 0.91 | NR4A2 (0.52) | NR4A2MAOBMAOAMEN1KMT2A | |
| SCHEMBL8551278 | 0.91 | MAOB (0.52) | NR4A2MAOBMEN1KMT2ASMPD1 | |
| SCHEMBL8551050 | 0.90 | MAOB (0.48) | NR4A2MAOBMAOAMEN1KMT2A | |
| SCHEMBL7907422 | 0.90 | NR4A2 (0.58) | NR4A2MAOBMAOAMEN1KMT2A | |
| SCHEMBL7901169 | 0.90 | NR4A2 (0.58) | NR4A2MAOBMAOAMEN1KMT2A | |
| SCHEMBL8545953 | 0.87 | MAOB (0.51) | NR4A2MAOBMAOAMEN1KMT2A | |
| SCHEMBL8546264 | 0.87 | MAOB (0.51) | NR4A2MAOBKMT2ASMPD1PTPN1 | |
| SCHEMBL8550294 | 0.86 | MAOB (0.50) | NR4A2MAOBMAOAMEN1KMT2A | |
| SCHEMBL8549782 | 0.85 | MAOB (0.53) | NR4A2MAOBMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |