Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545953 | 0.91 | MAOB (0.51) | MAOBNR4A2SMPD1PTPN1HDAC1 | |
| SCHEMBL7901060 | 0.90 | NR4A2 (0.53) | MAOBNR4A2SMPD1PTPN1HDAC1 | |
| SCHEMBL7901053 | 0.90 | NR4A2 (0.53) | MAOBNR4A2SMPD1PTPN1HDAC1 | |
| SCHEMBL8545812 | 0.89 | MAOB (0.51) | MAOBNR4A2SMPD1PTPN1GPR132 | |
| SCHEMBL8549880 | 0.89 | MAOB (0.51) | MAOBNR4A2SMPD1PTPN1GPR132 | |
| SCHEMBL8548524 | 0.88 | MAOB (0.50) | MAOBNR4A2SMPD1PTPN1GPR132 | |
| SCHEMBL8546173 | 0.87 | MAOB (0.47) | MAOBNR4A2SMPD1PTPN1HDAC1 | |
| SCHEMBL8543419 | 0.86 | MAOB (0.55) | MAOBNR4A2SMPD1PTPN1GPR132 | |
| SCHEMBL8551050 | 0.86 | MAOB (0.48) | MAOBNR4A2SMPD1PTPN1HDAC1 | |
| SCHEMBL8549185 | 0.86 | NR4A2 (0.54) | MAOBNR4A2SMPD1PTPN1GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |